About iMet-Q

iMet-Q (intelligent Metabolomic Quantitation) is an automated tool with friendly user interfaces for quantifying metabolites in full-scan liquid chromatography-mass spectrometry (LC-MS) data. It has a complete quantitation procedure for noise removal, peak detection and peak alignment. In addition to accurate quantitation, iMet-Q provides the charge states and isotope ratios of detected compounds. It accepts input data in netCDF, mzXML, and mzML format and exports quantitation results in csv and txt format.


Hui-Yin Chang et al., "iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination", PloS one. 2016;11(1):e0146112. PubMed PMID: 26784691.

Important Notices

  • How to install iMet-Q (pdf)
  • The user guide of iMet-Q (pdf)
  • The files of standard metabolite mixture (download)
  • For users using Windows Vista or Windows 7, please make sure that the "Privilege Level" of Compatibility has been checked. (Right click on the icon of iMet-Q->Compatibility->Privilege Level: Run this program as an administrator)

Tutorial Video

System Requirement

  The recommended system environment is:
  1. Operating System: Windows XP, Windows 7, 8 and Windows Server 2008, 2012
  2. CPU: Intel ® CPU 2.40 GHz
  3. HDD: 50GB or more free space
  4. Memory: 4GB or more
  5. Microsoft .Net Framework: .Net 4.0 or higher
  6. Screen Resolution: 1024*768 or higher

Update Infromation

2015.10.02 V1.001 is available
  • Solve the problem of nonconsecutive scan number.
2015.07.01 V1.000 is available
  • iMet-Q is officially on-line.


1. Why can't I open iMet-Q after installation?
  Reply: It might be due to the system environment setting problem. Here are three possible solutions:
            a. Right click on the shortcut of iMet-Q and slect the property. Then, check "Run as administrator" mode" in the compatibility.

           b. Install .Net Framework 4.0.
           c. Change another computer.